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NAV1.6 VOLTAGE-GATED SODIUM CHANNEL
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DeCS
Descriptor
English
:
NAV1.6 Voltage-Gated Sodium Channel
Descriptor
Spanish
:
Canal de Sodio Activado por Voltaje NAV1.6
Descriptor
Portuguese
:
Canal de Sódio Disparado por Voltagem NAV1.6
Synonyms
English
:
NAV1.6 Voltage Gated Sodium Channel
SCN8A Sodium Channel alpha Subunit
Type 8 Voltage Gated Sodium Channel
Type 8 Voltage-Gated Sodium Channel
Voltage Gated Sodium Channel Type 8
Voltage Gated Sodium Channel Type 8 Subunit alpha
Voltage-Gated Sodium Channel Type 8
Voltage-Gated Sodium Channel Type 8 Subunit alpha
Tree Number:
D12.776.157.530.400.875.750.600
D12.776.543.550.450.875.750.600
D12.776.543.585.400.875.750.600
D12.776.631.960.600
Definition
English
:
A voltage-gated
sodium
channel subtype found widely expressed in
neurons
of the central and peripheral nervous systems. Defects in the SCN8A gene which codes for the alpha subunit of this
sodium
channel are associated with
ATAXIA
and cognitive deficits.
Entry Combination - descr/qualif
English
:
NAV1.6 Voltage-Gated Sodium Channel
/
antagonists & inhibitors
use
Voltage-Gated Sodium Channel Blockers
NAV1.6 Voltage-Gated Sodium Channel
/
agonists
use
Voltage-Gated Sodium Channel Agonists
History Note
English
:
2013
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
54952
Unique Identifier:
D062557
Occurrence in VHL
:
Similar:
DeCS